Article
Association between ABCA7 gene polymorphisms and Parkinson's disease susceptibility in a northern Chinese Han population.
Neuroscience letters - 27 Jul 2022
Yang Zhengjie, Xue Li, Li Chengqian, Li Mingjuan, Xie Anmu
Abstract excerpt
OBJECTIVE: As a typical member of the ABC transporter superfamily, ABCA7 has been shown to play an important role in stalling the pathogenesis of neurodegenerative disorders through maintaining the normal microglial function, regulating cellular responses to inflammation and ER stress, and modulating lipid metabolism. Variants in the ABCA7 locus have been hypothesized to be correlated with the genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
