Article
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
The EMBO journal - 4 May 2020
Nürenberg-Goloub Elina, Kratzat Hanna, Heinemann Holger, Heuer André, Kötter Peter, Berninghausen Otto, Becker Thomas, Tampé Robert, Beckmann Roland
Abstract excerpt
Ribosome recycling by the twin-ATPase ABCE1 is a key regulatory process in mRNA translation and surveillance and in ribosome-associated protein quality control in Eukarya and Archaea. Here, we captured the archaeal 30S ribosome post-splitting complex at 2.8 Å resolution by cryo-electron microscopy. The structure reveals the dynamic behavior of structural motifs unique to ABCE1, which ultimately leads to ribosome...
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