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Article

Characterizing the role of porin mutations in susceptibility of beta lactamase producing Klebsiella pneumoniae isolates to ceftaroline and ceftaroline-avibactam.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Apr 2020

Khalid Ali, Lubián Alicia Fajardo, Ma Li, Lin Ruby C Y, Iredell Jonathan R

Abstract excerpt

OBJECTIVES: Evaluate the role of porins in the susceptibility of Klebsiella pneumoniae to ceftaroline and ceftaroline-avibactam. METHODS: Susceptibility to ceftaroline and ceftaroline-avibactam was tested by broth microdilution method in Klebsiella pneumoniae isolates (n = 65), including isogenic mutants (n = 30) and clinical isolates (n = 35), with different outer membrane porin defects in the presence or...

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Identifiers

PMID: 32061861
DOI: 10.1016/j.ijid.2020.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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