Article
Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal.
Scientific reports - 13 Feb 2020
Perdigão João, Gomes Pedro, Miranda Anabela, Maltez Fernando, Machado Diana, Silva Carla, Phelan Jody E, Brum Laura, Campino Susana, Couto Isabel, Viveiros Miguel, Clark Taane G, Portugal Isabel
Abstract excerpt
Portugal is a low incidence country for tuberculosis (TB) disease. Now figuring among TB low incidence countries, it has since the 1990s reported multidrug resistant and extensively drug resistant (XDR) TB cases, driven predominantly by two strain-types: Lisboa3 and Q1. This study describes the largest characterization of the evolutionary trajectory of M/XDR-TB strains in Portugal, spanning a time-period of two...
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