Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3.

doi:10.3390/genes13060990

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Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3.

Genes - 31 May 2022

Shuaib Yassir A, Utpatel Christian, Kohl Thomas A, Barilar Ivan, Diricks Margo, Ashraf Nadia, Wieler Lothar H, Kerubo Glennah, Mesfin Eyob A, Diallo Awa Ba, Al-Hajoj Sahal, Ndung'u Perpetua, Fitzgibbon Margaret M, Vaziri Farzam, Sintchenko Vitali, Martinez Elena, Viegas Sofia O, Zhou Yang, Azmy Aya, Al-Amry Khaled, Godreuil Sylvain, Varma-Basil Mandira, Narang Anshika, Ali Solomon, Beckert Patrick, Dreyer Viola, Kabwe Mwila, Bates Matthew, Hoelscher Michael, Rachow Andrea, Gori Andrea, Tekwu Emmanuel M, Sidze Larissa K, Jean-Paul Assam A, Beng Veronique P, Ntoumi Francine, Frank Matthias, Diallo Aissatou Gaye, Mboup Souleymane, Tessema Belay, Beyene Dereje, Khan Sadiq N, Diel Roland, Supply Philip, Maurer Florian P, Hoffmann Harald, Niemann Stefan, Merker Matthias

Abstract excerpt

Mycobacterium tuberculosis complex (MTBC) Lineage 3 (L3) strains are abundant in world regions with the highest tuberculosis burden. To investigate the population structure and the global diversity of this major lineage, we analyzed a dataset comprising 2682 L3 strains from 38 countries over 5 continents, by employing 24-loci mycobacterial interspersed repetitive unit-variable number of tandem repeats genotyping...

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PMID: 35741753
DOI: 10.3390/genes13060990
PMCID: PMC9222951

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