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Article

Frequent mutation of hypoxia-related genes in persistent pulmonary hypertension of the newborn.

Respiratory research - 13 Feb 2020

Wang Mingbang, Zhuang Deyi, Mei Mei, Ma Haiyan, Li Zixiu, He Fusheng, Cheng Guoqiang, Lin Guang, Zhou Wenhao

Abstract excerpt

AIMS: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by sustained high levels of pulmonary vascular resistance after birth with etiology unclear; Arterial blood oxygen saturation of Tibetan newborns at high latitudes is higher than that of Han newborns at low latitudes, suggesting that genetic adaptation may allow sufficient oxygen to confer Tibetan populations with resistance to...

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Identifiers

PMID: 32054482
DOI: 10.1186/s12931-020-1314-5
PMCID: PMC7020588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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