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In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan

13 Feb 2020

Abstract excerpt

Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of action but a wide range of different responses depending on the patient. Exploring this collection of mechanisms is one of the clues for a future personalized medicine. The Therapeutic Performance...

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PMID: 32053711
DOI: 10.1371/journal.pone.0228926

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