Article
Adipose tissue macrophages: their role in adipose tissue remodeling.
Journal of leukocyte biology - 1 Jul 2010
Suganami Takayoshi, Ogawa Yoshihiro
Abstract excerpt
The adipose tissue secretes a large number of bioactive substances, adipocytokines, which may be involved in a variety of physiologic and pathologic processes. Unbalanced production of pro- and anti-inflammatory adipocytokines seen in visceral fat obesity contributes critically to the development of the metabolic syndrome. Evidence has accumulated indicating that obesity is associated with a state of chronic,...
Topics
- Adipocytes
- Adipose Tissue
- Animals
- Homeostasis
- Humans
- Hypertrophy
- Inflammation
- Insulin Resistance
- Macrophages
- Obesity
- Phenotype
