Antagonistic pleiotropy conceals molecular adaptations in changing environments.

Abstract excerpt

The importance of positive selection in molecular evolution is debated. Evolution experiments under invariant laboratory conditions typically show a higher rate of nonsynonymous nucleotide changes than the rate of synonymous changes, demonstrating prevalent molecular adaptations. Natural evolution inferred from genomic comparisons, however, almost always exhibits the opposite pattern even among closely related...

Topics

• Acclimatization
• Adaptation, Physiological
• Evolution, Molecular
• Mutation
• Selection, Genetic