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Subtelomeric Transcription and its Regulation

6 Feb 2020

Abstract excerpt

The subtelomeres, highly heterogeneous repeated sequences neighboring telomeres, are transcribed into coding and noncoding RNAs in a variety of organisms. Telomereproximal subtelomeric regions produce non-coding transcripts i.e., ARRET, αARRET, subTERRA, and TERRA, which function in telomere maintenance. The role and molecular mechanisms of the majority of subtelomeric transcripts remain unknown. This review...

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PMID: 32035903
DOI: 10.1016/j.jmb.2020.01.026

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