Article
[Clinical significance of common leukemia gene mutations in patients with acute promyelocytic leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2013
Yin Jia, Sun Ai-Ning, Tian Xiao-Peng, Tian Hong, Wang Rong-Xian, Yang Zhen, Wang Xiu-Li, Wu De-Pei, Qiu Hui-Ying, Pan Jin-Lan, Cen Jian-Nong, Liang Jian-Ying, Chen Su-Ning
Abstract excerpt
This study was aimed to explore whether multiple common gene mutations of leukemia synergistically involved in acute promyelocytic leukemia (APL) pathogenesis, and to investigate their relevance to clinical features, cytogenetics and molecular risk stratification. 84 specimens of admitted de novo APL patients from February 2005 to October 2010 were collected, the gene mutations of bone marrow mononuclear cells...
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