Article
HLA associations with infliximab-induced liver injury.
The pharmacogenomics journal - 1 Oct 2020
Bruno Christopher D, Fremd Brandon, Church Rachel J, Daly Ann K, Aithal Guruprasad P, Björnsson Einar S, Larrey Dominique, Watkins Paul B, Chow Christina R
Abstract excerpt
Biomarkers that are able to identify patients at risk of drug-induced liver injury (DILI) after treatment with infliximab could be important in increasing the safety of infliximab use. We performed a genetic analysis to identify possible human leukocyte antigen (HLA) associations with DILI in European Caucasian users of infliximab in a retrospective study of 16 infliximab-DILI patients and 60 matched controls. In...
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