Article
Cathelicidin LL-37 (an antimicrobial peptide)-induced colistin dependence in Acinetobacter baumannii.
Diagnostic microbiology and infectious disease - 1 Apr 2020
Lee Ji-Young, Hong Yoon-Kyoung, Ko Kwan Soo
Abstract excerpt
In this study, we demonstrated the development of colistin dependence in Acinetobacter baumannii isolates after exposure to the human cationic antimicrobial peptide LL-37. The LL-37-induced colistin-dependent mutants showed susceptibility to many other antibiotics and IS1595 or ATTT insertions in LpxACD.
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