Article
Common variation in FAM155A is associated with diverticulitis but not diverticulosis.
Scientific reports - 3 Feb 2020
Reichert Matthias C, Kupcinskas Juozas, Schulz Antje, Schramm Christoph, Weber Susanne N, Krawczyk Marcin, Jüngst Christoph, Casper Markus, Grünhage Frank, Appenrodt Beate, Zimmer Vincent, Tamelis Algimantas, Lukosiene Jaune I, Pauziene Neringa, Kiudelis Gediminas, Jonaitis Laimas, Goeser Tobias, Malinowski Maciej, Glanemann Matthias, Kupcinskas Limas, Lammert Frank
Abstract excerpt
Colonic diverticulosis is a very common condition. Many patients develop diverticulitis or other complications of diverticular disease. Recent genome-wide association studies (GWAS) consistently identified three major genetic susceptibility factors for both conditions, but did not discriminate diverticulititis and diverticulosis in particular due the limitations of registry-based approaches. Here, we aimed to...
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