Article
Association study of candidate genes with obesity and metabolic traits in antipsychotic-treated patients with first-episode psychosis over a 2-year period.
Journal of psychopharmacology (Oxford, England) - 1 May 2020
Gassó Patricia, Arnaiz Joan Albert, Mas Sergi, Lafuente Amalia, Bioque Miquel, Cuesta Manuel J, Díaz-Caneja Covadonga M, García Clemente, Lobo Antonio, González-Pinto Ana, Parellada Mara, Corripio Iluminada, Vieta Eduard, Castro-Fornieles Josefina, Mané Anna, Rodríguez Natalia, Boloc Daniel, Saiz-Ruiz Jerónimo, Bernardo Miguel
Abstract excerpt
AIMS: Patients with a first episode of psychosis (FEP) often display different metabolic disturbances even independently of drug therapy. However, antipsychotic (AP) treatment, especially with second-generation APs, is strongly linked to weight gain, which increases patients' risk of developing obesity and other metabolic diseases. There is an important genetic risk component that can contribute to the appearance...
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