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Article

Allele-Specific QTL Fine Mapping with PLASMA.

American journal of human genetics - 6 Feb 2020

Wang Austin T, Shetty Anamay, O'Connor Edward, Bell Connor, Pomerantz Mark M, Freedman Matthew L, Gusev Alexander

Abstract excerpt

Although quantitative trait locus (QTL) associations have been identified for many molecular traits such as gene expression, it remains challenging to distinguish the causal nucleotide from nearby variants. In addition to traditional QTLs by association, allele-specific (AS) QTLs are a powerful measure of cis-regulation that are concordant with traditional QTLs but typically less susceptible to...

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Identifiers

PMID: 32004450
DOI: 10.1016/j.ajhg.2019.12.011
PMCID: PMC7011109

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