Article
pmar1/phb homeobox genes and the evolution of the double-negative gate for endomesoderm specification in echinoderms.
Development (Cambridge, England) - 26 Feb 2020
Yamazaki Atsuko, Morino Yoshiaki, Urata Makoto, Yamaguchi Masaaki, Minokawa Takuya, Furukawa Ryohei, Kondo Mariko, Wada Hiroshi
Abstract excerpt
In several model animals, the earliest phases of embryogenesis are regulated by lineage-specific genes, such as Drosophila bicoid Sea urchin (echinoid) embryogenesis is initiated by zygotic expression of pmar1, a paired-class homeobox gene that has been considered to be present only in the lineage of modern urchins (euechinoids). In euechinoids, Pmar1 promotes endomesoderm specification by repressing the hairy...
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