Article
Structure-function correlation of micro1 for micromere specification in sea urchin embryos.
Mechanisms of development - 1 Jan 2000
Yamazaki Atsuko, Ki Sewon, Kokubo Tetsuro, Yamaguchi Masaaki
Abstract excerpt
The micromeres of sea urchin embryos have two functions: to promote the autonomous differentiation of skeletogenic cells and to induce endomesodermal tissues. Micromere specification is controlled by a double-repression gate consisting of two repressors, Pmar1 and HesC. Micro1/pmar1 encodes a transcriptional repressor with a paired-type N-terminal homeodomain and two C-terminal serine-rich repeats, each of which...
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