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Article

A novel gamma radiation-inactivated sabin-based polio vaccine

30 Jan 2020

Abstract excerpt

A concerted action on the part of international agencies and national governments has resulted in the near-eradication of poliomyelitis. However, both the oral polio vaccine (OPV) and the inactivated polio vaccine (IPV) have deficiencies which make them suboptimal for use after global eradication. OPV is composed of attenuated Sabin strains and stimulates robust immunity, but may revert to neurovirulent forms in...

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PMID: 31999745
DOI: 10.1371/journal.pone.0228006

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