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The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation

22 Jan 2020

Abstract excerpt

N 6-Methyladenosine (m6A) is the most abundant RNA modification in mammal mRNAs and increasing evidence suggests the key roles of m6A in human tumorigenesis. However, whether m6A, especially its 'reader' YTHDF1, targets a gene involving in protein translation and thus affects overall protein production in cancer cells is largely unexplored. Here, using multi-omics analysis for ovarian cancer, we identified a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31996915
DOI: 10.1093/nar/gkaa048

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