Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The potential role of m6A reader YTHDF1 as diagnostic biomarker and the signaling pathways in tumorigenesis and metastasis in pan-cancer

27 Jan 2023

Abstract excerpt

m6A is an important RNA methylation in progression of various human cancers. As the m6A reader protein, YTHDF1 is reported to accelerate m6A-modified mRNAs translation in cytoplasm. It is highly expressed in various human cancers and contributes to the progression and metastasis of cancers. YTHDF1 was closely associated with poor prognosis and also used as a molecular marker for clinical diagnosis or therapy in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Structural Anomalies and Repair
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36707507
DOI: 10.1038/s41420-023-01321-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The potential role of m6A reader YTHDF1 as diagnostic biomarker and the signaling pathways in tumorigenesis and metastasis in pan-cancerPMID 36707507Read ↗

YTHDC1 serves as a potential therapeutic target and is linked with the immune microenvironment in Pan cancerSemantic proximity Read ↗

YTHDF1 Facilitates Lung Adenocarcinoma Progression via Promotion of EEF1G Translation in a m6A-Dependent MannerSemantic proximity Read ↗

Genetic identification of the m6A-related gene YTHDF3 as a putative biomarker for breast cancerSemantic proximity Read ↗

Pan-Cancer Analysis Identifies YTHDF2 as an Immunological and Prognostic BiomarkerSemantic proximity Read ↗

Systematic analysis of the expression profile and prognostic significance of m6A regulators and PD-L1 in hepatocellular carcinomaSemantic proximity Read ↗

YTHDF1 Promotes Cyclin B1 Translation through m6A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation.Semantic proximity Read ↗

Main N6-Methyladenosine Readers: YTH Family Proteins in CancersSemantic proximity Read ↗

The YTH Domain Family of N6‐Methyladenosine “Readers” in the Diagnosis and Prognosis of Colonic AdenocarcinomaSemantic proximity Read ↗

Exploring the role of m6A modification in cancerSemantic proximity Read ↗

Identification of the Signature Associated With m6A RNA Methylation Regulators and m6A-Related Genes and Construction of the Risk Score for Prognostication in Early-Stage Lung AdenocarcinomaSemantic proximity Read ↗

The three YTHDF paralogs and VIRMA are the major tumor drivers among the m <sup>6</sup> A core genes in a pan-cancer analysisSemantic proximity Read ↗

m6A reader YTHDF1 inhibits the growth of neuroblastoma in vitro and in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.