Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis

29 Jan 2020

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Glioma Diagnosis and Treatment
Share to Single-cell and spatial transcriptomics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31996845
DOI: 10.1038/s41586-020-1952-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIK3CA variants selectively initiate brain hyperactivity during gliomagenesisPMID 31996845Read ↗

PIK3CA Mutations Induce Neuronal Hyperactivity during Glioma Formation.Semantic proximity Read ↗

PIK3CA Mutations: Are They a Relevant Target in Adult Diffuse Gliomas?Semantic proximity Read ↗

PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastomaSemantic proximity Read ↗

Effect of PIK3CA variants on glioma-related epilepsy and response to treatment.Semantic proximity Read ↗

Somatic mutations in GLI3 can cause hypothalamic hamartoma and gelastic seizures.Semantic proximity Read ↗

Heterogeneity and excitability of <i>BRAF</i> <sup> <i>V600E</i> </sup> -induced tumors is determined by PI3K/mTOR-signaling state and <i>Trp53</i> -lossSemantic proximity Read ↗

Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profileSemantic proximity Read ↗

Glioma genetic profiles associated with electrophysiologic hyperexcitability.Semantic proximity Read ↗

Heterogeneity and excitability of BRAFV600E-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss.Semantic proximity Read ↗

A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors.Semantic proximity Read ↗

BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumorsSemantic proximity Read ↗

Glioma genetic profiles associated with electrophysiologic hyperexcitabilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.