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Article

Human Genetic Susceptibility of Leprosy Recurrence.

Scientific reports - 28 Jan 2020

Uaska Sartori Priscila Verchai, Penna Gerson O, Bührer-Sékula Samira, Pontes Maria A A, Gonçalves Heitor S, Cruz Rossilene, Virmond Marcos C L, Dias-Baptista Ida M F, Rosa Patricia S, Penna Maria L F, Medeiros Fava Vinicius, Stefani Mariane M A, Távora Mira Marcelo

Abstract excerpt

Host genetic susceptibility to leprosy has been intensively investigated over the last decades; however, there are no studies on the role of genetic variants in disease recurrence. A previous initiative identified three recurrent cases of leprosy for which none of the M. leprae strains, as obtained in the first and the second diagnosis, had any known genomic variants associated to resistance to Multidrug therapy;...

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Identifiers

PMID: 31992776
DOI: 10.1038/s41598-020-58079-3
PMCID: PMC6987179

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