Estimating the relative recurrence risk ratio for leprosy in Karonga District, Malawi.

Abstract excerpt

Leprosy is a chronic disease caused by infection with Mycobacterium leprae. Susceptibility to leprosy is influenced by both genetic and non-genetic factors and the disease is known to cluster in families. One measure of genetic effect is the relative recurrence risk ratio, lambdaR. Estimates of this parameter can be inflated if environmental risk factors which also cluster in families, such as household contact,...

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