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Article

Recurrence of tuberculosis in a low-incidence setting: a retrospective cross-sectional study augmented by whole genome sequencing.

BMC infectious diseases - 7 Jun 2018

Parvaresh Laila, Crighton Taryn, Martinez Elena, Bustamante Andrea, Chen Sharon, Sintchenko Vitali

Abstract excerpt

BACKGROUND: The recurrence of tuberculosis (TB) disease in treated patients can serve as a marker of the efficacy of TB control programs. Recurrent disease represents either endogenous reactivation with the same strain of Mycobacterium tuberculosis due to non-compliance or inadequate therapy or exogenous reinfection with a new strain. Genotyping or whole genome sequencing (WGS) of M. tuberculosis isolates from...

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Identifiers

PMID: 29879906
DOI: 10.1186/s12879-018-3164-z
PMCID: PMC5992641

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