Article
Tumor microenvironment and metabolism in prostate cancer.
Seminars in oncology - 1 Apr 2014
Chiarugi Paola, Paoli Paolo, Cirri Paolo
Abstract excerpt
Prostate cancer is no longer viewed mostly as a disease of abnormally proliferating epithelial cells, but rather as a disease affecting the complex interactions between the cells of the prostate epithelial compartment and the surrounding stromal compartment in which they live. Indeed, the microenvironment in which tumor cells evolve towards an aggressive phenotype is highly heterogeneous, as it is composed of...
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