Myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis: Clinical Characteristics, Radiologic Clues, and Outcome.

doi:10.1016/j.ajo.2018.07.020

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Article

Myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis: Clinical Characteristics, Radiologic Clues, and Outcome.

American journal of ophthalmology - 1 Nov 2018

Chen John J, Flanagan Eoin P, Jitprapaikulsan Jiraporn, López-Chiriboga Alfonso Sebastian S, Fryer James P, Leavitt Jacqueline A, Weinshenker Brian G, McKeon Andrew, Tillema Jan-Mendelt, Lennon Vanda A, Tobin W Oliver, Keegan B Mark, Lucchinetti Claudia F, Kantarci Orhun H, McClelland Collin M, Lee Michael S, Bennett Jeffrey L, Pelak Victoria S, Chen Yanjun, VanStavern Gregory, Adesina Ore-Ofe O, Eggenberger Eric R, Acierno Marie D, Wingerchuk Dean M, Brazis Paul W, Sagen Jessica, Pittock Sean J

Abstract excerpt

PURPOSE: To characterize the clinical phenotype of myelin oligodendrocyte glycoprotein antibody (MOG-IgG) optic neuritis. DESIGN: Observational case series. METHODS: Setting: Multicenter. Patient/Study Population: Subjects meeting inclusion criteria: (1) history of optic neuritis; (2) seropositivity (MOG-IgG binding index > 2.5); 87 MOG-IgG-seropositive patients with optic neuritis were included (Mayo Clinic, 76;...

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PMID: 30055153
DOI: 10.1016/j.ajo.2018.07.020
PMCID: PMC6371779

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