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Article

Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).

Acta neurologica Scandinavica - 1 Jun 2011

Asgari N, Owens T, Frøkiaer J, Stenager E, Lillevang S T, Kyvik K O

Abstract excerpt

In the past 10 years, neuromyelitis optica (NMO) has evolved from Devic's categorical clinical description into a broader disease spectrum. Serum IgG antibodies have been identified in NMO patients with the water channel aquaporin-4 (AQP4) as their main target antigen. AQP4 antibodies/NMO-IgG have been shown to be a highly specific and moderately sensitive serum biomarker for NMO. The immunopathology of NMO...

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Source

Identifiers

PMID: 20880299
DOI: 10.1111/j.1600-0404.2010.01416.x

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).PMID 20880299Read ↗

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NMO‐IgG: A Specific Biomarker for Neuromyelitis OpticaSemantic proximity Read ↗

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Comparisons of clinical phenotype, radiological and laboratory features, and therapy of neuromyelitis optica spectrum disorder by regions: update and challenges.Semantic proximity Read ↗

Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders.Semantic proximity Read ↗

The prevalence and clinical phenotype of dual seropositive neuromyelitis optica spectrum disorders at a national reference center in South Asia.Semantic proximity Read ↗

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