Article

Mechanical activation drives tenogenic differentiation of human mesenchymal stem cells in aligned dense collagen hydrogels

2021-11-25

Abstract excerpt

Tendons are force transmitting mechanosensitive tissues predominantly comprised of highly aligned collagen type I fibres. In this study, the recently introduced gel aspiration-ejection method was used to rapidly fabricate aligned dense collagen (ADC) hydrogel scaffolds. ADCs provide a biomimetic environment compared to traditional collagen hydrogels that are mechanically unstable and comprised of randomly oriented...

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Identifiers and source

Literature Corpus work: 77cd3eed-93fe-5c2f-b115-7d88694af42c
DOI: 10.1101/2021.11.25.470026

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