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Article

Murine sca1/flk1-positive cells are not endothelial progenitor cells, but B2 lymphocytes.

Basic research in cardiology - 24 Jan 2020

Steffen Eva, Mayer von Wittgenstein Wolfgang Bernd Edziu, Hennig Marie, Niepmann Sven Thomas, Zietzer Andreas, Werner Nikos, Rassaf Tienush, Nickenig Georg, Wassmann Sven, Zimmer Sebastian, Steinmetz Martin

Abstract excerpt

Circulating sca1+/flk1+ cells are hypothesized to be endothelial progenitor cells (EPCs) in mice that contribute to atheroprotection by replacing dysfunctional endothelial cells. Decreased numbers of circulating sca1+/flk1+ cells correlate with increased atherosclerotic lesions and impaired reendothelialization upon electric injury of the common carotid artery. However, legitimate doubts remain about the identity...

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Source

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Identifiers

PMID: 31980946
DOI: 10.1007/s00395-020-0774-6
PMCID: PMC6981106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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