Article
Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate.
Biomolecules - 21 Jan 2020
Baksheeva Viktoriia E, Nemashkalova Ekaterina L, Firsov Alexander M, Zalevsky Arthur O, Vladimirov Vasily I, Tikhomirova Natalia K, Philippov Pavel P, Zamyatnin Andrey A, Zinchenko Dmitry V, Antonenko Yuri N, Permyakov Sergey E, Zernii Evgeni Yu
Abstract excerpt
Neuronal calcium sensors are a family of N-terminally myristoylated membrane-binding proteins possessing a different intracellular localization and thereby targeting unique signaling partner(s). Apart from the myristoyl group, the membrane attachment of these proteins may be modulated by their N-terminal positively charged residues responsible for specific recognition of the membrane components. Here, we examined...
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