Central precocious puberty: Recent advances in understanding the aetiology and in the clinical approach.

Abstract excerpt

Central precocious puberty (CPP) results from early activation of the hypothalamic-pituitary-gonadal (HPG) axis. The current state of knowledge of the complex neural network acting at the level of the hypothalamus and the GnRH neuron to control puberty onset has expanded, particularly in the context of molecular interactions. Along with these advances, the knowledge of pubertal physiology and pathophysiology has...

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• Gonadotropin-Releasing Hormone
• Mutation
• Puberty
• Puberty, Precocious
• Ubiquitin-Protein Ligases