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Article

T-cell receptor diversity as a prognostic biomarker in melanoma patients.

Pigment cell & melanoma research - 1 Jul 2020

Charles Julie, Mouret Stephane, Challende Isabelle, Leccia Marie-Therese, De Fraipont Florence, Perez Solene, Plantier Nadia, Plumas Joel, Manuel Manuarii, Chaperot Laurence, Aspord Caroline

Abstract excerpt

There is increasing evidence that T-cell receptor (TCR) repertoire diversity can be a predictive biomarker of immune responses in cancer patients. However, the characteristics of the T-cell repertoire together with its prognostic significance in melanoma patients and impact on disease progression remain unknown. We investigated the combinatorial TCR repertoire diversity by semi-quantitative multi-N-plex PCR in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31971658
DOI: 10.1111/pcmr.12866

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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