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Article

Circulating CD8+ T-cell repertoires reveal the biological characteristics of tumors and clinical responses to chemotherapy in breast cancer patients

22 Aug 2018

Abstract excerpt

CD8 + T cells are primarily cytotoxic cells that provide immunological protection against malignant cells. Considerable evidence suggests that the T-cell repertoire is closely associated with the host immune response and the development of cancer. In this study, we explored the characteristics of the circulating CD8 + T-cell repertoire and their potential value in predicting the clinical response of breast cancer...

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PMID: 30167861
DOI: 10.1007/s00262-018-2213-1

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