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Article

Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility.

Development (Cambridge, England) - 22 Jan 2020

Xu Kaibiao, Yang Lele, Zhang Lan, Qi Huayu

Abstract excerpt

The development and maintenance of the correct morphology of sperm is important for their functions. Cellular morphogenesis of sperm occurs during the post-meiotic developmental stage; however, little is known about what coordinates this process. In the present study, we investigated the role of A-kinase anchoring protein 3 (AKAP3) during mouse spermiogenesis, using both mouse genetics and proteomics. It was...

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Identifiers

PMID: 31969357
DOI: 10.1242/dev.181057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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