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Article

Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.

Developmental biology - 15 Aug 2002

Miki Kiyoshi, Willis William D, Brown Paula R, Goulding Eugenia H, Fulcher Kerry D, Eddy Edward M

Abstract excerpt

A-kinase anchoring proteins (AKAPs) tether cyclic AMP-dependent protein kinases and thereby localize phosphorylation of target proteins and initiation of signal-transduction processes triggered by cyclic AMP. AKAPs can also be scaffolds for kinases and phosphatases and form macromolecular complexes with other proteins involved in signal transduction. Akap4 is transcribed only in the postmeiotic phase of...

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Source

Identifiers

PMID: 12167408
DOI: 10.1006/dbio.2002.0728

Genes

AKAP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.PMID 12167408Read ↗

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