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Adenylate Kinases 1 and 2 Are Part of the Accessory Structures in the Mouse Sperm Flagellum1

22 Jun 2006

Abstract excerpt

Proper sperm function depends on adequate ATP levels. In the mammalian flagellum, ATP is generated in the midpiece by oxidative respiration and in the principal piece by glycolysis. In locations where ATP is rapidly utilized or produced, adenylate kinases (AKs) maintain a constant adenylate energy charge by interconverting stoichiometric amounts of ATP and AMP with two ADP molecules. We previously identified...

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PMID: 16790685
DOI: 10.1095/biolreprod.106.053512

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