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Article

Genetic Study of Psoriasis Highlights its Close Link with Socioeconomic Status and Affective Symptoms.

The Journal of investigative dermatology - 1 Dec 2024

Heikkilä Anni, Sliz Eeva, Huilaja Laura, Reis Kadri, Palta Priit, Elnahas Abdelrahman G, Reigo Anu, Esko Tõnu, Laisk Triin, Teder-Laving Maris, Tasanen Kaisa, Kettunen Johannes

Abstract excerpt

Psoriasis is an inflammatory skin disease with an estimated heritability of around 70%. Previous GWASs have detected several risk loci for psoriasis. To further improve the understanding of the genetic risk factors impacting the disease, we conducted a discovery GWAS in FinnGen and a subsequent replication and meta-analysis with data from the Estonian Biobank and the UK Biobank; the study sample included 925,649...

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PMID: 38763176
DOI: 10.1016/j.jid.2024.03.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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