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Curcumin Affects HSP60 Folding Activity and Levels in Neuroblastoma Cells

19 Jan 2020

Abstract excerpt

The fundamental challenge in fighting cancer is the development of protective agents able to interfere with the classical pathways of malignant transformation, such as extracellular matrix remodeling, epithelial-mesenchymal transition and, alteration of protein homeostasis. In the tumors of the brain, proteotoxic stress represents one of the main triggering agents for cell transformation. Curcumin is a natural...

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PMID: 31963896
DOI: 10.3390/ijms21020661

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