Article
Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.
European journal of cancer (Oxford, England : 1990) - 1 Mar 2020
de Boo Leonora, Cimino-Mathews Ashley, Lubeck Yoni, Daletzakis Antonios, Opdam Mark, Sanders Joyce, Hooijberg Erik, van Rossum Annelot, Loncova Zuzana, Rieder Dietmar, Trajanoski Zlatko, Vollebergh Marieke, Sobral-Leite Marcelo, van de Vijver Koen, Broeks Annegien, van der Wiel Rianne, van Tinteren Harm, Linn Sabine, Horlings Hugo Mark, Kok Marleen
Abstract excerpt
BACKGROUND: The prognostic value of tumour-infiltrating lymphocytes (TILs) differs by breast cancer (BC) subtype. The aim of this study was to evaluate TILs in stage III BC in the context of BRCA1/2-like phenotypes and association with outcome and benefit of intensified platinum-based chemotherapy. PATIENTS AND METHODS: Patients participated in a randomised controlled trial of adjuvant intensified platinum-based...
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