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Article

Differential expression of major histocompatibility complex class I in subtypes of breast cancer is associated with estrogen receptor and interferon signaling.

Oncotarget - 24 May 2016

Lee Hee Jin, Song In Hye, Park In Ah, Heo Sun-Hee, Kim Young-Ae, Ahn Jin-Hee, Gong Gyungyub

Abstract excerpt

Tumor-infiltrating lymphocytes (TILs) in triple-negative breast cancer (TNBC) have a strong prognostic and predictive significance. However, the mechanism of TIL influx in TNBC is unclear. Expression of major histocompatibility complex class I (MHC I) on the tumor cell is essential for the effective killing of tumor by cytotoxic TILs. In our current study, human leukocyte antigen (HLA) expression was inversely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

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Share to Lymphocytes, Tumor-Infiltrating

Share to Receptors, Progesterone

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Source

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Identifiers

PMID: 27121061
DOI: 10.18632/oncotarget.8798
PMCID: PMC5058668

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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