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Article

Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans.

Pediatric research - 1 Jan 2009

Silverman Gary A, Luke Cliff J, Bhatia Sangeeta R, Long Olivia S, Vetica Anne C, Perlmutter David H, Pak Stephen C

Abstract excerpt

As an experimental system, Caenorhabditis elegans offers a unique opportunity to interrogate in vivo the genetic and molecular functions of human disease-related genes. For example, C. elegans has provided crucial insights into fundamental biologic processes, such as cell death and cell fate determinations, as well as pathologic processes such as neurodegeneration and microbial susceptibility. The C. elegans...

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Identifiers

PMID: 18852689
DOI: 10.1203/PDR.0b013e31819009b0
PMCID: PMC2731241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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