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Storage of cellular 5′ mRNA caps in P bodies for viral cap-snatching

1 Dec 2008

Abstract excerpt

The minus strand and ambisense segmented RNA viruses include multiple important human pathogens and are divided into three families, the Orthomyxoviridae, the Bunyaviridae, and the Arenaviridae. These viruses all initiate viral transcription through the process of "cap-snatching," which involves the acquisition of capped 5' oligonucleotides from cellular mRNA. Hantaviruses are emerging pathogenic viruses of the...

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PMID: 19047634
DOI: 10.1073/pnas.0807211105

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