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The mechanism of genome replication and transcription in bunyaviruses

12 Jan 2023

Abstract excerpt

Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority diseases requiring urgent development of medical countermeasures highlighting their high epidemic potential. While the viral large (L) protein containing the RNA-dependent RNA polymerase is a key enzyme in the viral replication cycle and...

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PMID: 36634042
DOI: 10.1371/journal.ppat.1011060

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