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Article

Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets.

Antiviral research - 1 Aug 2011

Govorkova Elena A, Marathe Bindumadhav M, Prevost Ashley, Rehg Jerold E, Webster Robert G

Abstract excerpt

Pandemic 2009 influenza A (H1N1) virus (H1N1pdm) is different from contemporary seasonal human viruses in that it can cause infection deep in the lungs of critical care patients. Here we establish a mammalian animal model and assessed the efficacy of the neuraminidase (NA) inhibitor oseltamivir treatment against H1N1pdm virus infection. Oseltamivir (25 mg/kg/day twice daily for 5 days) was orally administered to...

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Source

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Identifiers

PMID: 21635924
DOI: 10.1016/j.antiviral.2011.05.008
PMCID: PMC3148604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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