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Article

Role of pseudorabies virus Us3 protein kinase during neuronal infection.

Journal of virology - 1 Jul 2006

Olsen L M, Ch'ng T H, Card J P, Enquist L W

Abstract excerpt

The pseudorabies virus (PRV) Us3 gene is conserved among the alphaherpesviruses and encodes a serine/threonine protein kinase that is not required for growth in standard cell lines. In this report, we used a compartmented culture system to investigate the role of PRV Us3 in viral replication in neurons, in spread from neurons to PK15 cells, and in axon-mediated spread of infection. We also examined the role of...

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Identifiers

PMID: 16775327
DOI: 10.1128/JVI.00352-06
PMCID: PMC1488934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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