Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Novel Pathogenic Sequence Variants of the Mismatch Repair Genes During Screening for Lynch Syndrome in a Single Centre of Eastern Hungary.

Journal of gastrointestinal cancer - 1 Sept 2020

Kóder Gergely, Olasz Judit, Tanyi Janos L, George Erin, Tóth László, Antal-Szalmás Péter, Nagy Béla, Bubán Tamás, András Csilla, Urbancsek Hilda, Laczik Miklós, Csuka Orsolya, Damjanovich László, Tanyi Miklós

Abstract excerpt

INTRODUCTION: Lynch syndrome is an autosomal dominant disorder, most frequent leading to colon cancer. Identification of patients with Lynch syndrome and screening of their family members are available prevention approach that can significantly decrease mortality. Unfortunately, routine screening still does not belong to standard of care in Hungary. In this study, we performed a comprehensive screening in order...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Follow-Up Studies

Share to Hungary

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 31939059
DOI: 10.1007/s12029-020-00359-2
PMCID: PMC7399673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Novel Pathogenic Sequence Variants of the Mismatch Repair Genes During Screening for Lynch Syndrome in a Single Centre of Eastern Hungary.PMID 31939059Read ↗

Clinicopathological and molecular characterization of Brazilian families at risk for Lynch syndrome.Semantic proximity Read ↗

Update on Lynch syndrome genomics.Semantic proximity Read ↗

Identification of novel pathogenic MSH2 mutation and new DNA repair genes variants: investigation of a Tunisian Lynch syndrome family with discordant twinsSemantic proximity Read ↗

First description of mutational analysis of MLH1, MSH2 and MSH6 in Algerian families with suspected Lynch syndrome.Semantic proximity Read ↗

Molecular analysis of Iranian colorectal cancer patients at risk for Lynch syndrome: a new molecular, clinicopathological feature.Semantic proximity Read ↗

Lynch syndrome in the 21st century: clinical perspectives.Semantic proximity Read ↗

Analysis of mismatch repair gene mutations in Turkish HNPCC patients.Semantic proximity Read ↗

A Novel Stop-Gain Mutation in MSH2 Gene Among a Persian Family Fulfilling Classic Amsterdam Criteria for Lynch SyndromeSemantic proximity Read ↗

Screening for Lynch Syndrome in Cases with Colorectal Carcinoma from Mashhad.Semantic proximity Read ↗

A Previously Unrecognized Molecular Landscape of Lynch Syndrome in the Mexican PopulationSemantic proximity Read ↗

Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study.Semantic proximity Read ↗

Germline Genetic Features of Young Individuals With Colorectal Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.