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Article

Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.

Scientific reports - 14 Jan 2020

Emam Mehdi, Cánovas Angela, Islas-Trejo Alma D, Fonseca Pablo A S, Medrano Juan F, Mallard Bonnie

Abstract excerpt

Reactive Nitrogen Species (RNS) are a group of bactericidal molecules produced by macrophages in response to pathogens in a process called oxidative burst. Nitric oxide (NO-) is a member of RNS produced from arginine by inducible Nitric Oxide Synthase (iNOS) enzyme. The activity of iNOS and production of NO- by macrophages following stimulation is one of the indicators of macrophage polarization towards...

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Identifiers

PMID: 31937813
DOI: 10.1038/s41598-019-57089-0
PMCID: PMC6959288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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