Article

Transcriptomic signature and metabolic programming of bovine classical and nonclassical monocytes indicate distinct functional specializations

2020-11-01

Abstract excerpt

Similar to human monocytes, bovine monocytes can be split into CD14 + CD16 − classical and CD14 − CD16 + nonclassical monocytes (cM and ncM, respectively). Here, we present an in-depth analysis of their steady-state transcriptomes, highlighting pronounced functional specializations. Gene transcription indicates that pro-inflammatory and antibacterial processes are associated with cM, while ncM appear to be spe...

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Literature Corpus work: e6c3d58d-355f-511f-974f-efc5c047d10c
DOI: 10.1101/2020.10.30.362731

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