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Shiga toxin-producing Escherichia coli plasmid diversity reveals virulence potential and control opportunities in animal hosts

22 Jul 2025

Abstract excerpt

Shiga toxin-producing Escherichia coli (STEC) is a significant public health concern, with plasmids playing a key role in its pathogenicity. This study investigates the relationship between plasmid types, virulence genes, and host specificity in 96 STEC strains isolated from cattle, sheep, goats, and pigeons in Iran. We examined the distribution of plasmid-encoded virulence genes, including astA, cma, cba, rhsA1,...

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PMID: 40696010
DOI: 10.1038/s41598-025-11905-y

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